BMP promotes motility and represses growth of smooth muscle cells by activation of tandem
نویسنده
چکیده
The Rockefeller University Press $30.00 J. Cell Biol. Vol. 192 No. 1 171–188 www.jcb.org/cgi/doi/10.1083/jcb.201008060 JCB 171 Correspondence to Marlene Rabinovitch: [email protected] Abbreviations used in this paper: ANOVA, analysis of variance; AoSMC, aortic SMC; Apo, apolipoprotein; ARD, ankyrin repeat domain; C, -catenin; BMP, bone morphogenetic protein; BMPRII, BMP receptor II; Co-IP, coimmunoprecipitation; CSA, cross-sectional area; Dvl, disheveled; ERK, extracellular signal– related kinase; FN, fibronectin; ILK-1, integrin-linked kinase 1; IPAH, idiopathic PAH; OCT, optical coherence tomography; PA, pulmonary artery; PAEC, PA endothelial cell; PAH, pulmonary arterial hypertension; PCP, planar cell polarity; PRS, proline-rich sequence; ROCK I/II, Rho kinase I/II; SMC, smooth muscle cell; VSMC, vascular SMC; Wnt, wingless; WT, wild type. Introduction
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BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways
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